Homocysteine Response (Previously Folate, B6 & B12) same great product!
With Nourishing Beet Root, Homocysteine Response is crafted from 100% whole foods to help maintain healthy levels of homocysteine in the body. The formula is enriched by the inclusion of Beet Root, an excellent food source of the methyl donors, folate and betaine. Sufficient body stores of methyl donors ensure that homocysteine is converted back to the amino acid methionine. Elevated homocysteine levels are associated with fat accumulation and damage to various tissue and organ systems. In addition the methylation factors including folate, vitamin B-12 or betaine are helpful in promoting normal production of neurotransmitters like serotonin or in the maintenance of the myelin sheath.
Suggested Use: One tablet daily, or as needed.
Serving Size 1 Tablet
Servings per Container 90
Total Fat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0.1 mg
Total Carbohydrate . . . . . . . . . . . . . . . . . . . . . . . . . 66 mg
Dietary Fiber . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 mg
Sugars . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0 mg
Protein . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 mg
SOURCE; FOODSTATE AMOUNT
Vitamin B-6 . . . . . . . . . . (S. cerevisiae*; 125 mg) 25 mg
Folate . . . . . . . . . . . . . (Medicago sativa*; 80 mg) 800mcg
Vitamin B-12 . . . . . . . . . . (S. cerevisiae*; 12 mg) 60mcg
ADDITIONAL FOODS & EXTRACTS
Beet Root . . . . . . . . (naturally occurring Betaine) 75 mg
NATURALLY OCCURRING FOOD CONSTITUENTS
Bioactive Peptides, Enzymes, Chlorophyll, SOD, Glutathione, Beta Glucans, Lipoic Acid, Essential Trace Minerals, GABA, Glutamic Acid, Polysaccharides, CoQ10 and other Compounds.
Cellulose, Rice Bran, Vegetable Stearic Acid, Silica, Guar Gum, Pharmaceutical Glaze.
* FoodState 100% Food Concentrates
The National Institutes of Health, Office of Dietary Supplements states the following about B6, B 12 and Folate:
It performs a wide variety of functions in your body and is essential for your good health. For example, vitamin B6 is needed for more than 100 enzymes involved in protein metabolism. It is also essential for red blood cell metabolism. The nervous and immune systems need vitamin B6 to function efficiently, and it is also needed for the conversion of tryptophan (an amino acid) to niacin (a vitamin).
Vitamin B6 also helps maintain your blood glucose (sugar) within a normal range. When caloric intake is low your body needs vitamin B6 to help convert stored carbohydrate or other nutrients to glucose to maintain normal blood sugar levels.
Vitamin B6 and the nervous system
Vitamin B6 is needed for the synthesis of neurotransmitters such as serotonin and dopamine. These neurotransmitters are required for normal nerve cell communication. Researchers have been investigating the relationship between vitamin B6 status and a wide variety of neurologic conditions such as seizures, chronic pain, depression, headache, and Parkinson’s disease.
Vitamin B12 helps maintain healthy nerve cells and red blood cells. It is also needed to help make DNA, the genetic material in all cells. Vitamin B12 is also called cobalamin because it contains the metal cobalt.
Signs, symptoms, and health problems associated with vitamin B12 deficiency:
Characteristic signs, symptoms, and health problems associated with vitamin B12 deficiency include anemia, fatigue, weakness, constipation, loss of appetite, and weight loss.
Deficiency also can lead to neurological changes such as numbness and tingling in the hands and feet.
Additional symptoms of vitamin B12 deficiency are difficulty in maintaining balance, depression, confusion, dementia, poor memory, and soreness of the mouth or tongue.
Signs of vitamin B12 deficiency in infancy include failure to thrive, movement disorders, delayed development, and megaloblastic anemia.
Who else may need a vitamin B12 supplement to prevent a deficiency?
Individuals with pernicious anemia or with gastrointestinal disorders may benefit from or require a vitamin B12 supplement.
Older adults and vegetarians may benefit from a vitamin B12 supplement or an increased intake of foods fortified with vitamin B12.
Some medications may decrease absorption of vitamin B12. Chronic use of those medications may result in a need for additional vitamin B12.
Caution: Folic acid and vitamin B12 deficiency
Folic acid can correct the anemia that is caused by vitamin B12 deficiency. Unfortunately, folic acid will not correct the nerve damage also caused by vitamin B12 deficiency. Permanent nerve damage can occur if vitamin B12 deficiency is not treated. Folic acid intake from food and supplements should not exceed 1,000 ig daily in healthy individuals because large amounts of folic acid can trigger the damaging effects of vitamin B12 deficiency. Adults older than 50 years who take a folic acid supplement should ask their physician or qualified health care provider about their need for additional vitamin B12.
Do healthy young adults need a vitamin B12 supplement?
It is generally accepted that older adults are at greater risk of developing a vitamin B12 deficiency than younger adults. One study, however, suggests that the prevalence of vitamin B12 deficiency in young adults may be greater than previously thought. This study found that the percentage of subjects in three age groups (26-49 years, 50-64 years, and 65 years and older) with deficient blood levels of vitamin B12 was similar across all age groups but that symptoms of vitamin B12 deficiency were not as apparent in younger adults. This study also suggested that those who did not take a supplement containing vitamin B12 were twice as likely to be vitamin B12 deficient as supplement users, regardless of age group.
Folate is a water-soluble B vitamin that occurs naturally in food. Folic acid is the synthetic form of folate that is found in supplements and added to fortified foods.
When can folate deficiency occur?
A deficiency of folate can occur when an increased need for folate is not matched by an increased intake, when dietary folate intake does not meet recommended needs, and when folate excretion increases. Medications that interfere with the metabolism of folate may also increase the need for this vitamin and risk of deficiency.
Medical conditions that increase the need for folate or result in increased excretion of folate include:
pregnancy and lactation (breastfeeding)
Medications that interfere with folate utilization include:
anti-convulsant medications (such as dilantin, phenytoin and primidone)
metformin (sometimes prescribed to control blood sugar in type 2 diabetes)
sulfasalazine (used to control inflammation associated with Crohn’s disease and ulcerative colitis)
triamterene (a diuretic)
methotrexate (used for cancer and other diseases such as rheumatoid arthritis)
barbiturates (used as sedatives)
What are some common signs and symptoms of folate deficiency?
Folate deficient women who become pregnant are at greater risk of giving birth to low birth weight, premature, and/or infants with neural tube defects.
In infants and children, folate deficiency can slow overall growth rate.
In adults, a particular type of anemia can result from long term folate deficiency.
Other signs of folate deficiency are often subtle. Digestive disorders such as diarrhea, loss of appetite, and weight loss can occur, as can weakness, sore tongue, headaches, heart palpitations, irritability, forgetfulness, and behavioral disorders [1,20]. An elevated level of homocysteine in the blood, a risk factor for cardiovascular disease, also can result from folate deficiency.
Anti-convulsant medications such as dilantin increase the need for folate [26-27]. Anyone taking anti-convulsants and other medications that interfere with the body’s ability to use folate should consult with a medical doctor about the need to take a folic acid supplement.